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神奇验血 能预知你的将来

所属:社会热点 作者:Alice Park 来源:TIME时代周刊 阅读:3039 次 评论:2 条 [我要评论]  [+我要收藏]

小编摘要:如果可以让你预知将来,通过验血知道自己的寿命,你会如何选择呢?聪明的科学家们为我们提供了这样的一种可能。

A Blood Test to Predict Death? It Could Be Possible

 

Reporting in an early online publication of the Journal of the American Medical Association and at the European Society of Cardiology Congress, Johan Arnlov and his colleagues say that a certain enzyme that is measured in the blood may be linked to both heart disease and cancer, and therefore could serve as an early predictor of who is mostly likely to die from these diseases.

血液测试可能与心脏病和癌症都有着联系,也就是说验个血就能知道你得身体状况,也可以了解到谁会更有可能死于这些疾病。

In the study, which involved nearly 2,000 people enrolled in two separate long-term trials, Arnlov's team measured the levels of cathepsin S, an enzyme involved in breaking up proteins. They then tracked these volunteers for up to 12.5 years, and found that those with the highest levels of cathepsin S were more likely to die than those with lower, or about half those levels.

What is unique about the study is that it's the first to identify a marker associated with both heart disease and cancer, two of the leading killers of American adults. The effect remained strong even after the scientists adjusted for other factors that can contribute to heart- and cancer-related death, such as age, blood pressure, history of heart disease, diabetes and cholesterol levels.

cathepsin 组织蛋白酶  atheroslcerosis 动脉硬化 enzyme 酶

Arnlov decided to focus on cathepsin S because previous studies have linked the enzyme to atheroslcerosis, or the buildup and hardening of the arteries that increase the risk of heart disease. In animal studies, mice without the gene for cathepsin S developed less heart disease, and, interestingly, less cancer, compared with those animals that had the gene. Early studies in people have also showed that obese individuals tend to have higher levels of cathepsin S, and that if they lose weight, their levels go down.

"Cathepsin S is involved in several processes in the body," says Arnlov. "It is involved in the immune system, in regulating how [foreign material] is presented to the immune system, and it is highly expressed in [fat] tissue. It is involved in several crucial steps in the atherosclerotic process as well as in tumorgenesis."

But, he says, it's not clear exactly how cathepsin S might contribute to either heart disease or cancer. Nor is it obvious yet which tissues are producing the enzyme and whether there is a normal or healthy level. For example, the enzyme appears to be involved in inflammation, which can make plaques in the blood vessels unstable and trigger a heart attack, but it does not seem to be affected by levels of other inflammatory factors that have been linked to heart disease risk, such as C-reactive protein, or CRP.

通过组织蛋白酶S,可能就能测探出心脏病和癌症。

"To be honest, we don't know really what circulating levels of cathepsin S reflect," says Arnlov. "We can't be sure in what tissues it originates; we have no idea. So further studies need to elucidate what the circulating levels of cathepsin S really [mean]."

实际上,研究人员至今也不知道到底组织蛋白酶S能够反映到什么程度,他们也无法肯定它来自于什么样的组织。所以,还需要进一步研究。

He says it's too early to know whether cathepsin S can be useful in predicting who is at greatest risk of having heart disease, or whether levels of the enzyme in the blood can even become an early warning for cancer. But already pharmaceutical companies are targeting cathepsin S with compounds that block its activity. Those studies will likely provide answers to some critical questions about whether the enzyme really can be a biological crystal ball.

也许现在要说组织蛋白酶S在这方面是不是有效还言之过早,但是已经有医药公司瞄准了组织蛋白酶S。这些研究可能可以对“酶是不是生物水晶球”给出一个答案和澄清那些质疑。

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2011-09-05 17:16 编辑:Fionafyy
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  • sohelren 说:

    人是要接触了之后才会知道对方到底是不是合适自己,不能太主观地就给别人贴标签。

    2011-09-06 11:43 回复 支持(0) 反对(0) 沙发
  • sohelren 说:

    ⊙﹏⊙汗,发错咯

    2011-09-06 11:44 回复 支持(0) 反对(0) 板凳
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